In 1935 Regina, Lita, a young woman of gypsy ancestry, develops a passion for playing the guitar. After joining a jazz combo she quickly begins a life she couldn’t have imagined. In 1983, Lita’s granddaughter Elsa has become the lead singer, songwriter, and guitarist for the Regina punk band Speed Queen. Together with her punk rock husband and their new baby, they head to Seattle in a move that brings about unexpected personal changes. Though fifty years exist between grandmother and granddaughter, their circumstances and experiences reflect the daunting risks of a musician’s life where the pain of rejection, betrayal, and heartache must be managed alongside the responsibility of personal and professional commitments.