At a dinner party attended by the Dearly couple, Cruella de Vil expresses her dislike for animals; subsequently, the couple's new Dalmatian puppies disappear. The Dearly dogs are now among 97 puppies who were kidnapped or legally purchased from various owners, with the intention of skinning them for their fur. Through the co-operation of animals and the "Twilight Bark", the dogs are found in Suffolk, England, and a rescue ensues.