As one of North America's most unique ecologies, the Great Plains have fostered symbiotic relationships between humans and animals for millennia. Among these, Indigenous bonds to beavers, bison, and horses have been the subject of numerous anthropological and scientific surveys.

Beaver, Bison, Horse is an interdisciplinary account that centers on Indigenous knowledge and tradition. R. Grace Morgan's research, considered essential reading in the field, shows an ecological understanding that sustained Indigenous Peoples for thousands of years prior to colonial contact, with critical information on how the beaver manages water systems and protects communities from drought on the Plains.